HPV Prevention

Vaccination, safer sex and screening

Key points

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No method brings the chance of infection down to zero, but the vaccine, safer sex and screening can lower the risk considerably.

  • Having HPV does not mean that anyone has been unfaithful. The virus can stay in the body without symptoms for months or years, and it is usually impossible to tell when it was passed on or by whom.
  • HPV is not the same as AIDS. HPV and HIV (the virus that causes AIDS) are two different viruses. In 9 out of 10 people, HPV goes away or becomes undetectable within about two years; HIV does not follow this course.

The role of the vaccine, the HPV test and the Pap smear in prevention and screening

Primary prevention through the HPV vaccine and safer sex lowers the chance of infection. The HPV test can also be used as the first screening test for cervical cancer; it finds high-risk types of the virus even before cell changes develop.

The Pap smear is another cervical cancer screening method and looks for abnormal changes in the cells. Depending on the screening programme and your test results, a Pap smear may be done on its own, together with an HPV test, or as a follow-up test after it.

Vaccination and screening work together: the vaccine does not treat an existing infection and does not remove the need for screening.

HPV vaccine: how many doses, and the best time to get it

Filled circles show the doses needed; a dashed circle means one more dose may be needed.

Group
Number of doses
Recommendation
Ages 9 to 14
Number of doses

1 or 2 doses (if 2 doses are given, at least 6 months apart)

Recommendation

The best time to get the vaccine: before any exposure to the virus

Ages 15 to 20
Number of doses

1 or 2 doses

Recommendation

Vaccination is also recommended at this age

Age 21 and over
Number of doses

2 doses (6 months apart)

Recommendation

Based on your individual situation and your doctor’s advice; usually up to age 45

People with a weakened immune system or with HIV
Number of doses

At least 2 doses, 3 if possible

Recommendation

Need more complete protection

The number of doses depends on your age at the first dose

If you had your first dose before age 21, one or two doses are usually enough. If you start vaccination at age 21 or older, two doses are usually needed.

A single-dose schedule is not right for everyone

It depends on your age, immune status, the type of vaccine and the vaccination guidelines being followed. Decide on the number of doses with your doctor.

Does the vaccine still work if you already have HPV?

The vaccine does not treat an existing infection, but it may protect you against some HPV types you have not yet been infected with. Talk to your doctor about whether the vaccine would benefit you in your situation.

Which HPV types the vaccine covers

Gardasil 9 protects against 9 types of HPV: 6, 11, 16, 18, 31, 33, 45, 52 and 58.

What helps lower the chance of HPV spreading?

To lower your chance of getting HPV

  • Getting vaccinated at the right time
  • Limiting the number of sexual partners
  • Quitting smoking, to help your immune system work well

To lower the chance of passing it to your partner

  • Using condoms
  • Encouraging your partner to get vaccinated and examined
  • Seeing a doctor if you notice a lesion (an abnormal-looking area)

How much do condoms lower the risk of HPV?

Condoms lower the chance of passing on HPV, but they do not give complete protection, because they do not cover some areas of skin. In one study, using condoms every time was linked to about a 70% lower chance of infection.

Abstract drawing: a skin surface in contact, part of it under the translucent cover of a condom, with uncovered skin all around it. The area outside the cover is framed in gold. A condom lowers the risk of HPV transmission, but skin outside the cover may also be in contact.

HPV prevention for men

There is no routine screening test for men. The vaccine and condoms can lower the risk of getting HPV and passing it on.

What to do in a relationship with someone who has HPV

If your partner has HPV, talk about it without blame, and see your doctor to discuss whether you need the vaccine and what follow-up is needed.

How HPV spreads, and common myths

Main routes of transmission

  • Close skin contact during vaginal, anal or oral sex
  • Genital skin-to-skin contact, even without penetration
  • In rare cases, from mother to baby during childbirth

HPV has not been shown to spread this way

  • Swimming pool and hot tub water
  • Sitting on a public toilet
  • Sharing towels, clothes or dishes
  • Shaking hands and hugging

A positive HPV result does not mean someone cheated

HPV can stay in the body without symptoms for months or years. You can get it even if you have had sex with only one person. It is usually impossible to tell when the infection happened or who passed it on.

Cervical cancer screening: the second layer of HPV prevention

Screening with a Pap test (Pap smear; in the UK, a smear test) or an HPV test helps find cell changes early. These checks usually start between ages 21 and 25 and continue until age 65.

In standard programs, how often you are tested depends on the method chosen:

– HPV test on its own: every 5 years
– Pap test and HPV test together: every 5 years
– Pap test on its own: every 3 years

Your doctor will decide when to start, which test to use and how often to repeat it, based on your situation.

Can a supplement or a “prevention pill” replace the vaccine?

Supplements are not a substitute for the vaccine

No supplement, vitamin or “prevention pill” can replace the vaccine and screening.

A healthy lifestyle helps

Enough sleep, a balanced diet and quitting smoking support your immune system, but they do not guarantee that the infection will clear.

⚠️ Home remedies can cause harm

Putting vinegar, hair-removal paste or similar substances on a lesion can cause burns or infection. See a doctor to have warts checked and treated.

HPV prevention during pregnancy and with certain health conditions

Pregnancy and fertility

The HPV vaccine is not recommended during pregnancy. If you become pregnant between vaccine doses, the remaining doses are usually given after the pregnancy ends. Passing HPV to the baby during childbirth is rare.

Weakened immune system

If you have HIV, have had a transplant or take medicines that suppress the immune system, at least two doses of the vaccine are needed, and three if possible. Screening also needs to be followed up more closely.

Frequently asked questions about HPV prevention

Do sugar and sweets feed the virus?

No. This belief has no scientific basis. A balanced diet supports your general health, but no particular food feeds HPV.

No. HPV and HIV are two different viruses. In 9 out of 10 people, HPV goes away or becomes undetectable within about two years; HIV does not follow this course.

The HPV vaccine does not cause cancer, and its safety and effectiveness have been studied. If you have a history of allergies or a particular medical condition, talk to your doctor before the injection.

پرتره پروفسور مژگان کریمی‌زارچی
Author: Professor Mojgan Karimi-Zarchi
Gynecologic Oncologist

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